a great new spin on the popular names like Rylie, Kylie, etc. I first heard this name on a disney channel show (spelled Miley) my young cousin was watching and thought it was a great name.

Mylie and all its various spellings came to public attention through tv star/singer Miley Cyrus (born Destiny Hope Cyrus, nicknamed Miley because she was so "smiley"). It gained popularity because it already sounded like names like Kylie and Rylie that were popular at the time.
See Also: MyeLeigh, Maileigh, Mylee

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