| Prime Minister | Spouse |
|---|---|
| John Alexander Mac Donald | Isabella Clark Susan Agnes Bernard |
| Alexander Mackenzie | Helen Neil Jane Sym |
| John Joseph Caldwell Abbott | Mary Bethune |
| John Sparrow David Thompson | Annie Affleck |
| Mackenzie Bowell | Harriet Moore |
| Charles Tupper | Frances Morse |
| Wilfrid Laurier | Zoe Lafontaine |
| Robert Laird Borden | Laura Bond |
| Robert Meighen | Isabell J. Cox |
| William Lyon Mackenzie King | - |
| Richard Bedford Bennett | - |
| Louis Stephen St. Laurent | Jeanne Renault |
| John George Diefenbach | Edna Brower Olive Palmer |
| Lester Bowles Pearson | Maryon Moody |
| Pierre Elliot Trudeau | Margaret Sinclair |
| Charles Joseph Clark | Maureen McTeer |
| John Napier Turner | Geills McCrae Kilgour |
| Martin Brian Mulroney | Mila Pivnicki |
| A. Kim Campbell | Nathan Divinsky Howard Eddy |
| Joseph Jean Jacques Chrétien | Aline Chaine |